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- Is polyacrylamide hydrogel a permanent soft tissue filler?
- As a permanent soft tissue filler, the use of polyacrylamide hydrogel (PAAG) has been banned due to its myriad complications. However, a large number of symptomatic and asymptomatic patients whose breasts were augmented with the gel injection have continued to seek medical advice.
- What is polyacrylamide hydrogel (Paag)?
- Polyacrylamide hydrogel (PAAG) is a polymer synthesized from 2.5% acrylamide and 97.5% water ( 1 ). It was once considered a non-biodegradable hydrogel that was non-toxic, non-sensitizing, and non-teratogenic ( 2, 3 ).
- Does Paag decompose acrylamide monomers?
- Recent studies suggested that PAAG may decompose acrylamide monomers under multiple factors such as body fluids, various enzymes, and mechanical stimuli after injection into the body, with carcinogenic and toxic effects on the nervous and reproductive systems ( 1, 11 - 13 ).
