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- Why are polyacrylamide hydrogels used in cell mechanical and mechanobiological studies?
- Front. Mater., 22 July 2025 Polyacrylamide (PAM) hydrogels are commonly used as substrates for cell mechanical and mechanobiological studies because of their tunable stiffness and ease of handling.
- Are polyacrylamide hydrogels endorsed by the publisher?
- Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher. Polyacrylamide (PAM) hydrogels are commonly used as substrates for cell mechanical and mechanobiological studies because of their tunable stiffness and ease ...
- Are Pam hydrogels incompressible during AFM measurements?
- By combining Equations (1) or (2) with Equation (3), we obtained an average Poisson's ratio of 0.46, which suggests close to incompressible behavior of PAM hydrogels during AFM measurements and which is in agreement with the findings of a previous study on PAM that also combined AFM with bulk rheology ( Abidine et al., 2015 ).
- Do soft gels reach a plateau earlier than softest gels?
- These short term swelling experiments displayed similar trends as the AFM measurements: soft gels seemed to reach a plateau value earlier than softest gels, although for both gel compositions this occurred at earlier time points than for AFM (3 and 6 h for soft and softest gels, respectively).
