Polyacrylamide Bead Sensors for in vivo Quantification
Here, we describe and characterize cell-like polyacrylamide (PAAm) bead sensors with well-defined elastic properties and size for in vivo quantification of cell-scale stresses. The beads were injected into developing zebrafish embryos and their deformations were computationally analyzed to delineate spatio-temporal local acting stresses.
Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development. Nicole Traeber, Klemens Uhlmann, Salvatore Girardo, Gokul Kesavan, Katrin Wagner, Jens Friedrichs, Ruchi Goswami, Keliya Bai, Michael Brand, Carsten Werner, Daniel Balzani, Jochen Guck,
Polyacrylamide Bead Sensors for in vivo Quantification
Here, we describe and characterize cell-like polyacrylamide (PAAm) bead sensors with well-defined elastic properties and size for in vivo quantification of cell-scale stresses. The beads were injected into developing zebrafish embryos and their deformations were computationally analyzed to delineate spatio-temporal local acting stresses.
Mechanical stress exerted and experienced by cells during tissue morphogenesis and organ formation plays an important role in embryonic development. While techniques to quantify mechanical stresses in vitro are available, few methods exist for studying stresses in living organisms. Here, we describe and characterize cell-like polyacrylamide (PAAm) bead sensors with well-defined elastic
Aptamers Embedded in Polyacrylamide Nanoparticles: A Tool
We describe a new type of aptamer-based optical nanosensor which uses the embedding of target responsive oligonucleotides in porous polyacrylamide nanoparticles to eliminate nuclease instability. The latter is a common problem in the use of aptamer sensors in biological environments. These aptamers embedded in nanoparticles (AptaNPs) are proposed as a tool in real-time metabolite measurements
Polyacrylamide bead sensors for in vivo quantification of cell-scale stress during zebrafish development Technische Universität Dresden ; Johanna Zessin DANN-origami-templated synthesis of semoconducting polythiophene filaments Technische Universität Dresden ; Pengcheng Zhao
COMPAX - omicX
Simplifies the detection of pulsatile pressure propagation in the developing neural rod potentially originating from polarized midline cell divisions and continuous tissue flow. COMPAX consists of three steps: (1) users have to register two-dimensional confocal images of the deformed PAAm beads embedded in the tissue of a zebrafish embryo; (2) the undeformed configuration and approximate
Atomic spectrometry update. Industrial analysis: metals, chemicals and advanced materials. Simon Carter a, Andy S. Fisher * b, Phill S. Goodall c, Michael W. Hinds d, Steve Lancaster e and Sian Shore f a Hull Research & Technology Centre, BP, Saltend, East Yorkshire HU12 8DS b School of Geography, Earth and Environmental Sciences, University of Plymouth, Drake Circus, Plymouth, UK PL4 8AA c
Poster Abstract - 2025 - European Journal of Clinical
Photodynamic therapy was carried out by the apparatus Latus 662 nm (OOO «Aткyc», Russia) using of lightguide (diameter of 400 mm.) with output beam power of 1·4 kW with 8 minutes. exposure (summed energy 150–180j) after injection of 0·35% solution of radachlorin (OOO «Paдa‐Фapмa, Russia») in the amount of 1 mg/kg of body weight.
Monoclonal antibodies are also successfully used in the creation of biosensors that detect the sought-for substances in situ in real time, in which the binding of the antibody to the ligand in the biosensor leads to a detectable signal . However, the success of any immunochemical platform is primarily determined by the quality of the antibodies
Diverse Applications of Nanomedicine
The in vivo fate of NPs can potentially be a dynamic process, and thus, there is a need to understand nanobiokinetics (nanopharmacokinetics and pharmacodynamics), which may relate to unique and interesting toxicological responses of NPs. Nanomedicine is not limited to colloidal materials and technologies to evaluate them for in vivo applications.
Diagnostics of elastic properties of polymerizing polyacrylamide Korobov, A. I. , Filippova, O. E. , Kokshaisky, A. I. Faculty Of Physics, M.V. Lomonosov Moscow State University, Moscow, Russia. ABSTRACT Experimental results for the behavior of both linear and nonlinear elastic properties of polyacrylamide polymerization process are shown.
- Should medical waste be treated off-site or on-site?
- AHP synthesis (with inconsistency ratio of 0.01 < 0.1) revealed that, in total, the off-site treatment of medical waste was in much higher priority than the on-site treatment (64.1% versus 35.9%). According to the results of study it was concluded that the off-site central treatment can be considered as an alternative.
- Do on-site medical waste treatment systems have problems?
- For comparison of on-site and off-site facilities (due to non availability of an installed off-site facility) Analytical Hierarchy Process (AHP) was employed. The result indicated that most on-site medical waste treating systems have problems in financing, planning, determining capacity of installations, operation and maintenance.
- Can a municipality transport medical waste off-site?
- Only after on-site pre-treatment of medical waste will the municipality takes the responsibility for off-site transport of waste to the final disposal site. Nevertheless, according to the same Act of the regulation, small cities and villages are allowed to use off-site (central) facilities for treating their hazardous-infectious waste [ 29 ].
- Is open burning a safe way to dispose of medical waste?
- Despite the shortcomings of open burning as a method for treating medical waste, the World Health Organization (2019c) apparently recommends it as a last resort treatment option where there are no alternatives, recommending it as a “safe final disposal” method for sharps and infectious waste (World Health Organization, 2015).
