Experimental Polyacrylamide-induced Acute Injury in Rat Lung
We recently reported the first case of accidental aspiration of polyacrylamide occurring in a 26-year-old man. The patient developed severe airway obstruction and parenchymal lung damage and died. Autopsy revealed numerous polyacrylamide particles in his lungs, as well as extensive bronchiolar and alveolar damage. Gas chromatographic and mass spectrometric assessment of the lung tissue failed
Experimental polyacrylamide-induced acute injury in rat lung. (PMID:1424897) Abstract Citations This experimental study was performed to determine the nature and extent of damage to rat bronchial and alveolar epithelia following endotracheal instillation of polyacrylamide, hydrocarbon mixture (petroleum distillate), dodecane (C12H26), or
Experimental Polyacrylamide-induced Acute Injury in Rat Lung
Therefore, this experimental study in rat lung was undertaken to determine the nature and extent of acute injury to rat bronchiolar and alveolar epithelia following endotracheal instillation of polyacrylamide, hydrocarbon mixture (petroleum distillate), dodecane, or normal saline solution.
Laboratory and Animal Investigations. Experimental Polyacrylamide-induced Acute Injury in Rat Lung
Lung injury in acute experimental pancreatitis in rats
The pathogenesis of pancreatitis-related pulmonary injury was studied at the light- and electronmicroscopic level. Experimental pancreatitis was induced in rats by infusion of supramaximal doses of cerulein for 12 h. Investigations were carried out 3, 6, and 12 h after the start of infusion and 12, 48, and 72 h after the end of pancreatitis induction.
Lipopolysaccharide-induced acute lung injury in rats: comparative assessment of intratracheal instillation and aerosol inhalation. Liu F(1), Li W, Pauluhn J, Trübel H, Wang C. Author information: (1)Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing 100069, China.
Lung injury in acute experimental pancreatitis, in rats
In this study we report the functional change, in isolated perfused lungs from rats with cerulein-induced experimental pancreatitis. Rat lungs isolated immediately after the cerulein infusion demonstrated decreased pressor response, to angiotensin II (A II) and acute hypoxia (FIO2: 0.0). The lung wet- to dry-weight ratio was increased, as was the lung-leak index, consistent with high
Lung injury related to IgA-containing immune complexes was complement dependent but neutrophil independent.IncompanionstudieswithmouseIgG-con-taining immune complexes, acute lung injury also oc-curred and had morphological features similar to those associated with IgA-induced lung injury except that, in thecase ofIgGimmunecomplex-induced damage
Role of asymmetric dimethylarginine in rat acute lung
The aim of the present study was to establish a rat model of acute ischemic kidney injury by continually occluding the bilateral renal artery and renal veins, as well as to examine the role of asymmetric dimethylarginine (ADMA) in acute lung injury (ALI) induced by acute kidney injury (AKI). In total,
Randomized experimental study. The study aimed to investigate the therapeutic efficacy and molecular mechanisms of A-68930 in a rat model of spinal cord injury (SCI)–induced acute lung injury (ALI).
Sulfur dioxide reduces lipopolysaccharide-induced acute
Endotoxin-induced acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are consequences of acute respiratory failure. Although the mortality rate associated with this syndrome has declined recently, ARDS remains one of the major causes of pulmonary and non-pulmonary morbidity in patients after hospital
e e ect of betanin on a rat paraquat-induced acute lung injury (ALI) model was investigated. Paraquat was injected intraperitoneally at a single dose of mg/kg body weight, and betanin ( and mg/kg/d) was orally administered days before and days a er paraquat administration. Rats were sacri ced hours a er the last betanin dosage, and lung tissue and
