Effect of patterned polyacrylamide hydrogel on morphology
Effect of patterned polyacrylamide hydrogel on morphology and orientation of cultured NRVMs I. Sanzari a, E. J. Humphreyb, F. Dinellic, C. Terraccianob, T. Prodromakis aUniversity of Southampton, Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, Southampton, SO17 1BJ, UK
Effect of patterned polyacrylamide hydrogel on morphology and orientation of cultured NRVMs. that patterned Parylene C films could be effectively used as a mask for directly copolymerizing proteins on polyacrylamide hydrogel (PAm). In this work, we have proved the applicability of this technique for studying the effect such platforms render
Effect of patterned polyacrylamide hydrogel on morphology
We recently demonstrated that patterned Parylene C films could be effectively used as a mask for directly copolymerizing proteins on polyacrylamide hydrogel (PAm). In this work, we have proved the applicability of this technique for studying the effect such platforms render on neonatal rat ventricular myocytes (NRVMs). Firstly, we have characterised topographically and mechanically the
We recently demonstrated that patterned Parylene C films could be effectively used as a mask for directly copolymerizing proteins on polyacrylamide hydrogel (PAm). In this work, we have proved the applicability of this technique for studying the effect such platforms render on neonatal rat ventricular myocytes (NRVMs). Firstly, we have characterised topographically and mechanically the
Tuning the Range of Polyacrylamide Gel Stiffness
Effect of patterned polyacrylamide hydrogel on morphology and orientation of cultured NRVMs. Scientific Reports 2025, 8 (1) DOI: 10.1038/s41598-018-30360-6. Ranganathan Parthasarathy, Anil Misra, Linyong Song, Qiang Ye, Paulette Spencer.
The results show that the morphology of PAM solution prepared with deionized water exhibited a uniform three‐dimensional network structure. Both divalent metal ions and suspended substances have significant effects on PAM morphology and viscosity, but the effect of suspended substances is larger than that of divalent metal ions.
Geometric microenvironment directs cell morphology
Polyacrylamide hydrogels featuring a combinatorial, micropatterned array of posts with varied shape, width, and spacing were produced using a one-step technique. Substrates were covalently modified with collagen and seeded with D1 ORL UVA mesenchymal stem cells. Patterning was shown to direct several quantitative measures of cell morphology.
Effect of patterned polyacrylamide hydrogel on morphology and orientation of cultured NRVMs. Scientific Reports 2025, 8 (1) DOI: 10.1038/s41598-018-30360-6. Ranganathan Parthasarathy, Anil Misra, Linyong Song, Qiang Ye, Paulette Spencer.
Fabrication of topographically patterned hydrogel
The first goal of this work was to develop a new method for fabricating topographically patterned hydrogels for use as engineered microenvironments for cells. Polyacrylamide gels were cast from silicon masters by a process that involved ultrasonically vibrating the master during polymerization.
Polyvinyl alcohol (PVA) hydrogel and stem cell therapy have been widely used in wound healing. However, the lack of bioactivity for PVA and security of stem therapy limited their application. In this study, an adipose-derived stem cells (ADSCs)-seeded PVA dressing (ADSCs/PVA) was prepared for wound healing. One side of the PVA dressing was modified with photo-reactive gelatin (Az-Gel) via
Shape Morphable Hydrogel/Elastomer Bilayer for Implanted
Direct fabrication of a three-dimensional (3D) structure using soft materials has been challenging. The hybrid bilayer is a promising approach to address this challenge because of its programable shape-transformation ability when responding to various stimuli. The goals of this study are to experimentally and theoretically establish a rational design principle of a hydrogel/elastomer bilayer
The change in surface morphology of poly (AAm-co-NaAc) (T) hydrogel with incorporation of microcrystalline cellulose (MCC) and nanohybrid filler ([email protected] 3) is explored with their scanning electron micrographs.Moreover, the morphological change of MCC/poly (AAm-co-NaAc)/GO (L) and MCC/poly (AAm-co-NaAc)/r-GO (L) nanocomposite hydrogels are also examined to interpret the effect of
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