Mechanical Properties of a Reversible, DNA-Crosslinked
Download Citation | Mechanical Properties of a Reversible, DNA-Crosslinked Polyacrylamide Hydrogel | Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In
DNA-crosslinked polyacrylamide gels are polymeric electrolytes by virtue of the fact that DNA is negatively charged in an aqueous solution. As such, their mechanical properties can be altered by electrophoretic and electro-osmotic effects. Hybridization of single-stranded DNA with single-stranded sections of the crosslinks provides a novel
Mechanical Properties of DNA-Crosslinked Polyacrylamide
Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In this system, three DNA strands replace traditional chemical crosslinkers.
Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In this system, three DNA strands replace traditional chemical crosslinkers. In contrast to thermoset chemically crosslinked polyacrylamide, the new hydrogel is thermoreversible; crosslink dissociation without the addition of heat is also feasible by
Structural properties of scaffolds: Crucial parameters
Core tip: Application of stem cells in tissue engineering and regenerative medicine has attracted many researchers and it is considered as a hot topic of research. The research was mostly aimed towards the fabrication of a suitable scaffold with appropriate physical, chemical, biological and mechanical properties to guide the differentiation of stem cells to specific lineages of interest.
Mechanical properties of a reversible, DNA-crosslinked polyacrylamide hydrogel. Meta-DNA: synthetic biology via DNA nanostructures and hybridization reactions: Momentum noise in vacuum tunneling transducers: Multiscaffold DNA origami nanoparticle waveguides. Noise rise in nondegenerate parametric amplifiers: A nonintrusive method of measuring
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polyacrylamide gels are common for resolving DNA fragments of 50 - 2,000 bp sizes. The focus of this guide is on separations using acrylamide. Polyacrylamide gels are composed of long linear polyacrylamide chains crosslinked with bis-acrylamide (bis) to create a network of pores interspersed between bundles of polymer.
M. Tobiason*, E. Graugnard, W. L. Hughes; Design and Operation of an Autocatalytic, Seesaw-Gate Inspired DNA Network, poster presentation at The 19th International Conference on DNA Computing and Molecular Programming (DNA19) (Tempe, Arizona; Sept. 22-27,2013) Elton Graugnard, Operation of a DNA Nanomachine in Human Serum and Blood, invited oral presentation at the 2013 Idaho INBRE Conference
Advances in Bioactive Hydrogels to Probe and Direct Cell
Advanced cell culture techniques are increasingly needed to better understand basic cell physiology, predict in vivo response, and engineer de novo functional tissue substitutes. Toward this concept, hydrogels have emerged as biomimetic in vitro culture systems that allow cells to be grown in or on user-defined microenvironments that recapitulate many critical aspects of native tissue
Introduction. Atopic dermatitis (AD) is a common inflammatory skin disease, with a lifetime prevalence up to 20% (Drislane & Irvine, 2025; Weidinger et al., 2025).Impaired skin permeability barrier, which is largely provided by the stratum corneum (SC), is an important etiological factor in AD (Elias & Schmuth, 2009; Kezic et al., 2014).SC, the outermost skin layer is comprised of terminally
Structural properties of scaffolds: Crucial parameters
Core tip: Application of stem cells in tissue engineering and regenerative medicine has attracted many researchers and it is considered as a hot topic of research. The research was mostly aimed towards the fabrication of a suitable scaffold with appropriate physical, chemical, biological and mechanical properties to guide the differentiation of stem cells to specific lineages of interest.
Human mesenchymal stem cells cultured in stiffer gels developed bone-like behaviour, showing that the rheological properties of the gel can control cell differentiation. No enzymatic4, chemical5,6
- What factors affect the performance of polyacrylamide-based friction reducers?
- An important variable that highly affects the performance of polyacrylamide-based friction reducers is ion content. Performance, therefore, becomes dependent on both the ion type (cationic, anionic, monovalent or divalent) and the concentration present in the source water (Xu et al., 2016).
- Does dry polyacrylamide friction reducer work for slick water?
- Sanders M, Felling K, Thomson S, et al. Dry polyacrylamide friction reducer: not iust for slick water [Z]. SPE Hydraulic Fracturing Technology Conference, 2016, SPE-179146-MS. Kameneva MV. Microrheological effects of drag-reducing polymers in vitro and in vivo [J]. Int J Eng Sci. 2012;59:168–83.
- What is a friction reducer (polyacrylamide)?
- Due to the large volumes of water used, a friction reducer (polyacrylamide) is added to the fluid package to reduce the pumping energy required for the operation. The presence of the friction-reducing polymer (polyacrylamide) can reduce the friction loss and required pressures by as much as 60%.
- Which acrylamide polymers are used in hydraulic fracturing?
- Cationic, anionic, nonionic, and zwitterionic acrylamide polymers and copolymers can be synthesized as desired. Anionic PAM is the most widely used reducer with excellent DR performance and low cost for hydraulic fracturing of shale gas formations. Polyacrylamide FRs are generally provided in dry powder and emulsion.
